Gardella, Thomas J: search on Z-Library

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1

Total synthesis and structure–activity relationship studies of a series of selective G protein inhibitors

Xiong, Xiao-Feng, Zhang, Hang, Underwood, Christina R., Harpsøe, Kasper, Gardella, Thomas J., Wöldike, Mie F., Mannstadt, Michael, Gloriam, David E., Bräuner-Osborne, Hans, Strømgaard, Kristian

Journal:

Nature Chemistry

Year:

2016

Language:

english

File:

PDF, 2.68 MB

english, 2016

2

PTH/PTHrP Receptor Signaling, Allostery, and Structures

Sutkeviciute, Ieva, Clark, Lisa J., White, Alex D., Gardella, Thomas J., Vilardaga, Jean-Pierre

Journal:

Trends in Endocrinology & Metabolism

Year:

2019

Language:

english

File:

PDF, 3.61 MB

english, 2019

3

Multitechnique surface spectroscopic studies of plasma-modified polymers II: H2O/Ar plasma-modified polymethylmethacrylate/polymethacrylic acid copolymers

Hook, Thomas J., Gardella, Joseph A., Salvati, Lawrence

Journal:

Journal of Materials Research

Year:

1987

Language:

english

File:

PDF, 1.02 MB

english, 1987

4

Structure-function studies with recombinant PTH/PTHrP receptors

Harald Jüppner, Ernestina Schipani, Gino V. Segre, Abdul-Badi Abou-Samra, Thomas J. Gardella

Journal:

Journal of Bone and Mineral Metabolism

Year:

1994

Language:

english

File:

PDF, 407 KB

english, 1994

5

Backbone modification of a polypeptide drug alters duration of action in vivo

Cheloha, Ross W, Maeda, Akira, Dean, Thomas, Gardella, Thomas J, Gellman, Samuel H

Journal:

Nature Biotechnology

Year:

2014

Language:

english

File:

PDF, 351 KB

english, 2014

6

Surface spectroscopic studies of poly(methyl methacrylate) (PMMA) and modified PMMA surfaces

Lawrence Salvati Jr., Thomas J. Hook, Joseph A. Gardella Jr., Roland L. Chin

Journal:

Polymer Engineering & Science

Year:

1987

Language:

english

File:

PDF, 598 KB

english, 1987

7

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

Ferrandon, Sébastien, Feinstein, Timothy N, Castro, Marian, Wang, Bin, Bouley, Richard, Potts, John T, Gardella, Thomas J, Vilardaga, Jean-Pierre

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 931 KB

english, 2009

8

Retromer terminates the generation of cAMP by internalized PTH receptors

Feinstein, Timothy N, Wehbi, Vanessa L, Ardura, Juan A, Wheeler, David S, Ferrandon, Sebastien, Gardella, Thomas J, Vilardaga, Jean-Pierre

Journal:

Nature Chemical Biology

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

9

Analysis of polymer surface structure by low-energy ion scattering spectroscopy

Hook, Thomas J., Schmitt, Robert L., Gardella, Joseph A., Salvati, Lawrence., Chin, Roland L.

Journal:

Analytical Chemistry

Year:

1986

Language:

english

File:

PDF, 796 KB

english, 1986

10

Actions of the Small Molecule Ligands SW106 and AH-3960 on the Type-1 Parathyroid Hormone Receptor

Carter, Percy H., Dean, Thomas, Bhayana, Brijesh, Khatri, Ashok, Rajur, Raj, Gardella, Thomas J.

Journal:

Molecular Endocrinology

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

11

Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism

Liu, Shi, Jean-Alphonse, Frederic G., White, Alex D., Wootten, Denise, Sexton, Patrick M., Gardella, Thomas J., Vilardaga, Jean-Pierre, Gellman, Samuel H.

Journal:

Journal of the American Chemical Society

Year:

2019

Language:

english

File:

PDF, 1.23 MB

english, 2019

12

Inverse agonism and the PTH/PTHrP receptor

Robert Gensure, Percy H. Carter, Thomas J. Gardella

Journal:

International Congress Series

Year:

2003

Language:

english

File:

PDF, 301 KB

english, 2003

13

Mechanisms of Ligand Binding to the Parathyroid Hormone (PTH)/PTH-Related Protein Receptor: Selectivity of a Modified PTH(1–15) Radioligand for Gα S -Coupled Receptor Conformations

Dean, Thomas, Linglart, Agnes, Mahon, Matthew J., Bastepe, Murat, Jüppner, Harald, Potts, John T., Gardella, Thomas J.

Journal:

Molecular Endocrinology

Year:

2006

Language:

english

File:

PDF, 366 KB

english, 2006

14

Receptor selectivity from minimal backbone modification of a polypeptide agonist

Liu, Shi, Cheloha, Ross W., Watanabe, Tomoyuki, Gardella, Thomas J., Gellman, Samuel H.

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.09 MB

english, 2018

15

Knockin mouse with mutant Gα11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors

Roszko, Kelly L., Bi, Ruiye, Gorvin, Caroline M., Bräuner-Osborne, Hans, Xiong, Xiao-Feng, Inoue, Asuka, Thakker, Rajesh V., Strømgaard, Kristian, Gardella, Thomas, Mannstadt, Michael

Journal:

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

16

G protein–coupled receptor modulation with pepducins: moving closer to the clinic

Patricia Dimond, Kenneth Carlson, Michel Bouvier, Craig Gerard, Lei Xu, Lidija Covic, Anika Agarwal, Oliver P. Ernst, Jay M. Janz, Thue W. Schwartz, Thomas J. Gardella, Graeme Milligan, Athan Kuliopul

Journal:

Annals of the New York Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 626 KB

english, 2011

17

Molecular properties of the PTH/PTHrP receptor

Thomas J Gardella, Harald Jüppner

Journal:

Trends in Endocrinology & Metabolism

Year:

2001

Language:

english

File:

PDF, 184 KB

english, 2001

18

Engineering of Therapeutic Polypeptides through Chemical Synthesis: Early Lessons from Human Parathyroid Hormone and Analogues

Dong, Suwei, Shang, Shiying, Li, Jianfeng, Tan, Zhongping, Dean, Thomas, Maeda, Akira, Gardella, Thomas J., Danishefsky, Samuel J.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 2.42 MB

english, 2012

19

Secondary ion formation from functional polymer systems in static secondary ion mass spectrometry

Kevin J. Hook, Thomas J. Hook, Joseph H. Wandass, Joseph A. Gardella Jr.

Journal:

Applied Surface Science

Year:

1990

Language:

english

File:

PDF, 1.13 MB

english, 1990

20

The (1–14) Fragment of Parathyroid Hormone (PTH) Activates Intact and Amino-Terminally Truncated PTH-1 Receptors

Luck, Michael D., Carter, Percy H., Gardella, Thomas J.

Journal:

Molecular Endocrinology

Year:

1999

Language:

english

File:

PDF, 3.50 MB

english, 1999

21

[ACM Press the third ACM symposium - Not Known (1973..-..)] Proceedings of the third ACM symposium on Data communications and Data networks Analysis and design - DATACOMM '73 - A loop network for general purpose data communications in a heterogeneous world

Hassing, Thomas E., Hampton, Raymond M., Bailey, Gerald W., Gardella, Robert S.

Year:

1973

Language:

english

File:

PDF, 802 KB

english, 1973

22

New Copy Number Variations in Schizophrenia

Magri, Chiara, Sacchetti, Emilio, Traversa, Michele, Valsecchi, Paolo, Gardella, Rita, Bonvicini, Cristian, Minelli, Alessandra, Gennarelli, Massimo, Barlati, Sergio, Burne, Thomas

Journal:

Year:

2010

Language:

english

File:

PDF, 982 KB

english, 2010

23

Parathyroid hormone and parathyroid hormone-related peptide, and their receptors

Robert C. Gensure, Thomas J. Gardella, Harald Jüppner

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 1.09 MB

english, 2005

24

Solid-state analysis of eumelanin biopolymers by electron spectroscopy for chemical analysis

Clark, Michael B., Gardella, Joseph A., Schultz, Thomas M., Patil, Dilip G., Salvati, Lawrence.

Journal:

Analytical Chemistry

Year:

1990

Language:

english

File:

PDF, 968 KB

english, 1990

25

C-Terminal Analogues of Parathyroid Hormone: Effect of C-Terminus Function on Helical Structure, Stability, and Bioactivity

Potetinova, Zhanna, Barbier, Jean-René, Suen, Tanya, Dean, Thomas, Gardella, Thomas J., Willick, Gordon E.

Journal:

Year:

2006

Language:

english

File:

PDF, 226 KB

english, 2006

26

Pharmacodynamic Actions of a Long-Acting PTH Analog (LA-PTH) in Thyroparathyroidectomized (TPTX) Rats and Normal Monkeys

Shimizu, Masaru, Joyashiki, Eri, Noda, Hiroshi, Watanabe, Tomoyuki, Okazaki, Makoto, Nagayasu, Miho, Adachi, Kenji, Tamura, Tatsuya, Potts, John T, Gardella, Thomas J, Kawabe, Yoshiki

Journal:

Journal of Bone and Mineral Research

Year:

2016

Language:

english

File:

PDF, 976 KB

english, 2016

27

Zinc(II)-mediated enhancement of the agonist activity of histidine-substituted parathyroid hormone(1–14) analogues

Percy H Carter, Thomas J Gardella

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2001

Language:

english

File:

PDF, 469 KB

english, 2001

28

Toward Parathyroid Hormone Minimization: Conformational Studies of Cyclic PTH(1−14) Analogues

Tsomaia, Natia, Pellegrini, Maria, Hyde, Kimberly, Gardella, Thomas J., Mierke, Dale F.

Journal:

Year:

2004

Language:

english

File:

PDF, 495 KB

english, 2004

29

Functional Evidence for an Intramolecular Side Chain Interaction between Residues 6 and 10 of Receptor-Bound Parathyroid Hormone Analogues †

Shimizu, Naoto, Petroni, Brian D., Khatri, Ashok, Gardella, Thomas J.

Journal:

Year:

2003

Language:

english

File:

PDF, 250 KB

english, 2003

30

Selective and Nonselective Inverse Agonists for Constitutively Active Type-1 Parathyroid Hormone Receptors: Evidence for Altered Receptor Conformations 1

Carter, Percy H., Petroni, Brian D., Gensure, Robert C., Schipani, Ernestina, Potts Jr., John T., Gardella, Thomas J.

Journal:

Year:

2001

Language:

english

File:

PDF, 341 KB

english, 2001

31

Changes in conserved region 2 of Escherichia coli σ70 affecting promoter recognition

Carey Waldburger, Thomas Gardella, Rex Wong, Miriam M. Susskind

Journal:

Journal of Molecular Biology

Year:

1990

Language:

english

File:

PDF, 952 KB

english, 1990

32

Studies of the N-Terminal Region of a Parathyroid Hormone-Related Peptide(1–36) Analog: Receptor Subtype-Selective Agonists, Antagonists, and Photochemical Cross-Linking Agents 1

Carter, Percy H., Jüppner, Harald, Gardella, Thomas J.

Journal:

Year:

1999

Language:

english

File:

PDF, 1.53 MB

english, 1999

33

Backbone-methylated Analogues of the Principle Receptor Binding Region of Human Parathyroid Hormone

Barbier, Jean-René, Gardella, Thomas J., Dean, Thomas, MacLean, Susanne, Potetinova, Zhanna, Whitfield, James F., Willick, Gordon E.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 753 KB

english, 2005

34

Phenotypic spectrum of GABRA1

Johannesen, Katrine, Marini, Carla, Pfeffer, Siona, Møller, Rikke S., Dorn, Thomas, Niturad, Christina, Gardella, Elena, Weber, Yvonne, Søndergård, Marianne, Hjalgrim, Helle, Nikanorova, Mariana, Beck

Journal:

Year:

2016

Language:

english

File:

PDF, 990 KB

english, 2016

35

Parathyroid hormone (1-34) and its analogs differentially modulate osteoblastic RANKL expression via PKA/PP1/PP2A and SIK2/SIK3-CRTC3 signaling

Ricarte, Florante R., Le Henaff, Carole, Kolupaeva, Victoria G., Gardella, Thomas J., Partridge, Nicola C.

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 1.41 MB

english, 2018

36

Repeat Cesarean Delivery: What Indications Are Recorded in the Medical Chart?

Mona T. Lydon-Rochelle, Carolyn Gardella, Vicky Cárdenas, Thomas R. Easterling

Journal:

Year:

2006

Language:

english

File:

PDF, 135 KB

english, 2006

37

Residue 19 of the Parathyroid Hormone: Structural Consequences †

Piserchio, Andrea, Shimizu, Naoto, Gardella, Thomas J., Mierke, Dale F.

Journal:

Year:

2002

Language:

english

File:

PDF, 482 KB

english, 2002

38

Cooperative Interaction of Arginine-19 and the N-Terminal Signaling Domain in the Affinity and Potency of Parathyroid Hormone †

Tsomaia, Natia, Shimizu, Masaru, Shimizu, Naoto, Gardella, Thomas J., Mierke, Dale F.

Journal:

Year:

2004

Language:

english

File:

PDF, 589 KB

english, 2004

39

PTH receptor-1 signalling—mechanistic insights and therapeutic prospects

Cheloha, Ross W., Gellman, Samuel H., Vilardaga, Jean-Pierre, Gardella, Thomas J.

Journal:

Nature Reviews Endocrinology (formerly Nature Clinical Practice Endocrinology & Metabolism)

Year:

2015

Language:

english

File:

PDF, 311 KB

english, 2015

40

Diphtheria Toxin- and GFP-Based Mouse Models of Acquired Hypoparathyroidism and Treatment With a Long-Acting Parathyroid Hormone Analog

Bi, Ruiye, Fan, Yi, Lauter, Kelly, Hu, Jing, Watanabe, Tomoyuki, Cradock, Jim, Yuan, Quan, Gardella, Thomas, Mannstadt, Michael

Journal:

Journal of Bone and Mineral Research

Year:

2016

Language:

english

File:

PDF, 7.28 MB

english, 2016

41

Calcium fluxes at the bone/plasma interface: Acute effects of parathyroid hormone (PTH) and targeted deletion of PTH/PTH-related peptide (PTHrP) receptor in the osteocytes

Dedic, Christopher, Hung, Tin Shing, Shipley, Alan M., Maeda, Akira, Gardella, Thomas, Miller, Andrew L., Pajevic, Paola Divieti, Kunkel, Joseph G., Rubinacci, Alessandro

Journal:

Year:

2018

Language:

english

File:

PDF, 2.08 MB

english, 2018

42

Amino-Terminal Modifications of Human Parathyroid Hormone (PTH) Selectively Alter Phospholipase C Signaling via the Type 1 PTH Receptor: Implications for Design of Signal-Specific PTH Ligands †

Takasu, Hisashi, Gardella, Thomas J., Luck, Michael D., Potts, John T., Bringhurst, F. Richard

Journal:

Year:

1999

Language:

english

File:

PDF, 99 KB

english, 1999

43

Allosteric interactions in the parathyroid hormone GPCRâarrestin complex formation

Clark, Lisa J., Krieger, James, White, Alex D., Bondarenko, Vasyl, Lei, Saifei, Fang, Fei, Lee, Ji Young, Doruker, Pemra, BÃ¶ttke, Thore, Jean-Alphonse, Frederic, Tang, Pei, Gardella, Thomas J., Xiao,

Journal:

Nature Chemical Biology

Year:

2020

File:

PDF, 12.49 MB

2020

44

Endocrinology: Adult and Pediatric || Parathyroid Hormone and the Parathyroid Hormone Receptor Type 1 in the Regulation of Calcium and Phosphate Homeostasis and Bone Metabolism

Gardella, Thomas J.

Year:

2016

Language:

english

File:

PDF, 7.08 MB

english, 2016

45

Progress, Paradox, and Potential : Parathyroid Hormone Research over Five Decades

JOHN T. POTTS, THOMAS J. GARDELLA

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 313 KB

english, 2007

46

Reply

Gardella, Elena, Beniczky, Sándor, Møller, Rikke S., Becker, Felicitas, Lemke, Johannes R., Syrbe, Steffen, Eiberg, Hans, Bast, Thomas, Steinhoff, Bernhard, Nürnberg, Peter, Gellert, Pia, Dahl, Hans A

Journal:

Annals of Neurology

Year:

2016

Language:

english

File:

PDF, 49 KB

english, 2016

47

Amino-Terminal Parathyroid Hormone Fragment Analogs Containing α,α-di-alkyl Amino Acids at Positions 1 and 3

Naoto Shimizu, Thomas Dean, Ashok Khatri, Thomas J Gardella

Journal:

Journal of Bone and Mineral Research

Year:

2004

Language:

english

File:

PDF, 128 KB

english, 2004

48

A mutant Escherichia coli σ70 subunit of RNA polymerase with altered promoter specificity

Thomas Gardella, Henry Moyle, Miriam M. Susskind

Journal:

Journal of Molecular Biology

Year:

1989

Language:

english

File:

PDF, 1.46 MB

english, 1989

49

Multitechnique surface spectroscopic studies of plasma-modified polymers I: H2O/Ar plasma-modified polymethylmethacrylates

Hook, Thomas J., Gardella, Joseph A., Salvati, Lawrence

Journal:

Journal of Materials Research

Year:

1987

Language:

english

File:

PDF, 1.57 MB

english, 1987

50

Enhanced Activity in Parathyroid Hormone-(1–14) and -(1–11): Novel Peptides for Probing Ligand-Receptor Interactions 1

Shimizu, Masaru, Carter, Percy H., Khatri, Ashok, Potts, John T., Gardella, Thomas J.

Journal:

Year:

2001

Language:

english

File:

PDF, 168 KB

english, 2001

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